AOD-9604
Advanced Obesity Drug 9604
AOD-9604 is a modified fragment of human growth hormone (HGH) specifically designed to have the fat-reducing effects of HGH without the negative side effects on blood sugar or growth. It corresponds to the C-terminal portion of HGH.
Buy AOD-9604 at Peptide PalacePurity
99%+
Molecular Weight
1815.08 g/mol
Administration
Subcutaneous injection
Storage
Store at -20°C
Mechanism of Action
AOD-9604 mimics the lipolytic (fat-burning) effects of natural HGH while not affecting IGF-1 levels or causing hyperglycemia. It stimulates lipolysis and inhibits lipogenesis, promoting fat breakdown without the growth-promoting effects.
Sequence:
Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe Chemical Structure
Research Areas
- Obesity treatment
- Fat metabolism
- Cartilage repair
- Osteoarthritis
- Metabolic disorders
Potential Benefits
- Targeted fat loss
- No effect on blood sugar
- Potential cartilage benefits
- No growth effects
- Well-tolerated
Research Dosing Guidelines
For research purposes only. Not for human consumption.
Typical Dose
300-500 mcg
Frequency
Once daily
Duration
12-20 weeks
Administration
Subcutaneous injection, preferably on empty stomach
Best administered in the morning on an empty stomach. Avoid food for 30 minutes after.
Reconstitution Calculator
U-100 Insulin Syringe
12.0 units
2500 mcg/ml
0.120 ml
12.0 IU
16
For research and educational purposes only. Always follow proper reconstitution and sterile handling protocols.
AOD-9604 vs Full-Length HGH: Key Differences
AOD-9604 is a fragment of human growth hormone (amino acids 177-191), specifically engineered to isolate the fat-burning properties while eliminating growth-related side effects.
Fragment vs Full Hormone
| Factor | AOD-9604 (Fragment) | Full-Length HGH |
|---|---|---|
| Fat loss | Yes (lipolysis + anti-lipogenesis) | Yes |
| Muscle growth | No | Yes |
| IGF-1 elevation | No | Significant |
| Blood sugar impact | None | Can cause insulin resistance |
| Water retention | Minimal | Significant |
| Joint/bone effects | Potential cartilage benefit | Growth effects on bone and cartilage |
| Cost | Lower | Much higher |
AOD-9604 represents a targeted approach for researchers specifically interested in fat metabolism without the systemic effects of growth hormone therapy.
Potential Side Effects
- Injection site reactions
- Headache (rare)
- Generally well tolerated
Storage Requirements
Store at -20°C. Reconstituted at 2-8°C.
Research References
- [1]AOD9604 and Lipid Metabolism (2001)Emerging Evidence Population: ob/ob mice
AOD-9604 stimulated lipolysis and inhibited lipogenesis in adipose tissue without affecting IGF-1 or insulin levels.
Limitations: Genetically obese mouse model; limited applicability to diet-induced obesity
- [2]Increase of Fat Oxidation and Weight Loss in Obese Mice (2001)Emerging Evidence Population: ob/ob obese mice
Chronic AOD-9604 treatment increased fat oxidation and produced significant weight reduction in obese mice.
Limitations: Genetic obesity model; no human dosing data established
Frequently Asked Questions
What is AOD-9604?
AOD-9604 is a modified fragment of human growth hormone corresponding to the C-terminal portion (amino acids 177-191), specifically designed to retain the fat-reducing effects of HGH without negative side effects on blood sugar or growth. It represents a targeted approach to fat metabolism research.
What are the potential research benefits of AOD-9604?
Research suggests AOD-9604 may promote targeted fat loss by stimulating lipolysis and inhibiting lipogenesis, without affecting blood sugar or IGF-1 levels. It has also shown potential benefits for cartilage repair in osteoarthritis research.
How is AOD-9604 typically dosed in research?
AOD-9604 is typically administered at 300-500 mcg once daily via subcutaneous injection, preferably on an empty stomach. Research cycles generally span 12-20 weeks, with administration recommended in the morning followed by fasting for 30 minutes.
What are the side effects of AOD-9604?
AOD-9604 is generally well tolerated in research settings. Potential side effects are minimal and may include injection site reactions and rare occurrences of headache.
How should AOD-9604 be stored?
AOD-9604 should be stored at -20°C in lyophilized form for long-term preservation. Once reconstituted, the solution should be refrigerated at 2-8°C and used promptly.
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Buy at Peptide PalaceRelated Topics
Peptide Hormones and Their Functions
Peptide hormones are hydrophilic signaling molecules that bind cell surface receptors, triggering intracellular cascades via second messengers like cAMP and calcium.
Structural Differences Between Peptides and Proteins
The critical distinction lies in tertiary structure: proteins possess stable hydrophobic cores that drive folding, while peptides remain flexible conformational ensembles.
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